La regeneración ósea guiada (ROG) actualmente es considerada una terapia de gran importancia en Implantología para promover la regeneración de hueso en defectos óseos maxilares con la finalidad de crear un lecho adecuado para el posicionamiento de implantes. La ROG se basa en el uso de membranas reabsorbibles y no reabsorbibles en combinación con biomateriales de relleno como hueso autólogo, homólogo, heterólogo o materiales aloplásticos con funciones de barrera mecánica, tendientes a excluir de la zona de reparación células epiteliales y conjuntivas, permitiendo la invasión de células osteoprogenitoras. En este artículo se presenta el caso clínico de un paciente al que se le realizó aumento vertical y horizontal de cresta ósea alveolar mediante regeneración ósea guiada en asociación con la colocación de implantes oseointegrados.

Guide Bone Regeneration has been used widely in implantology for enhancing bone healing to optimize implant placements in the maxillary. The GBR is a technique that uses resorbable and non-resorbable membranes in combination with other filling biomaterials as autologous, homologous or heterologous bone graft, or aloplastic materials as mechanic barriers that prohibit the migration of connective and epithelial cells, enabling the osteogenic cells invasion in bone defects. In the present study a clinic case of vertical and horizontal augmentation of alveolar ridge with guided bone regeneration in association with dental implants was reported.

In many cases chronic atypical odontalgia make patients visit several different specialists' surgeries, being unable to find the reason or the suitable treatment for the pain. We present three clinical cases in which a fissure in the tooth crown is proved to be the cause of the chronic atypical odontalgia. We think that when this fissure deepens it can affect dentin or pulp and thus not only cause this atypical pain for years but also result in tooth fracture in more than one case. We propose an early diagnosis of this type of etiology, the performance of an endodontic treatment and the placement of a protective metal-porcelain cap.

Las odontalgias atípicas crónicas obligan en muchos casos al paciente a ir saltando por consultas de diferentes especialistas, sin encontrar la causa, ni el tratamiento apropiado a su padecimiento. Presentamos tres casos clínicos en los cuales queda demostrada como causa de una odontalgia atípica crónica una fisura de la corona del diente. Pensamos que dicha fisura, cuando se prolonga en profundidad, puede afectar a dentina o pulpa y ser el motivo de ese dolor atípico durante incluso años, terminando en más de un caso en fractura del diente. Proponemos un diagnóstico temprano de este tipo de etiología, realización de una endodoncia y colocación de una funda metal-porcelana de protección.

Phenotypic diversity has been described in the central repeated region of the circumsporozoite protein (CSP) from Plasmodium vivax. Two sequences VK210 (common) and VK247 (variant) have been found widely distributed in P. vivax isolates from several malaria endemic areas around the world. A third protein variant called P. vivax-like showing a sequence similar to the simian parasite P. simio-ovale has also been described. Here, using an immunofluorescent test and specific monoclonal antibodies, we assessed the presence of two of these protein variants (VK210 and VK247) in laboratory produced sporozoite. Both sequences were found in parasite isolates coming from different geographic regions of Colombia. Interestingly, sporozoites carrying the VK247 sequence were more frequently produced in Anopheles albimanus than sporozoites with the VK210 sequence. This difference in sporozoites production was statistically significant (p <0.05, Kruskal-Wallis); not correlation was found with parameters as the total number of parasites or gametocytes in blood from human donors used to feed mosquitoes. Previous studies in the same region have shown a higher prevalence of anti-VK210 antibodies which in theory may suggest their role in blocking the development of sporozoites carrying the CSP VK210 sequence.